发明名称 |
Compositions and methods for screening for modulators of enzymatic activity |
摘要 |
The invention provides a method to screen for a modulator of enzymatic activity comprising the step of monitoring the association or dissociation of a pair of polypeptides which can associate as a dimer. The polypeptide pair comprises a first polypeptide comprising detection means and a site of post-translational modification and a second polypeptide comprising detection means.
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申请公布号 |
US7105307(B2) |
申请公布日期 |
2006.09.12 |
申请号 |
US20020161205 |
申请日期 |
2002.06.03 |
申请人 |
CYCLACEL, LTD. |
发明人 |
COLYER JOHN;WOOLFSON DEREK N.;LIGHTOWLER JOANNE |
分类号 |
G01N33/53;C07K14/00;C07K14/395;C12N15/62;C12Q1/00;G01N33/542;G01N33/573 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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