| 摘要 |
A process for the production of devices for the controlled release of acti ve substances, consisting of an active substance-containing matrix and an erodible mass of solids at least partially covering the matrix, with the thickness of the erodible mass across its extension being determined by thickness gradients, and the active substance-containing matrix itself being produced with thickness gradients which determine the thickness gradients of the erodible mass, is characterized in that in a first step the active substance-containing matrix is formed in the form of pressed articles having thickness gradients, and in a second step It is transferred onto a laminated tablet-compressing machine where it is compressed with the erodible mass.</S DOAB>
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