PREPARATION OF ACID ADDITION SALTS OF ZIPRASIDONE AND INTERMEDIATES THEREOF BY SOLID PHASE-GAS PHASE REACTIONS
摘要
A process for the preparation of an acid addition salt of ziprasidone base a nd intermediates thereof comprising exposing the ziprasidone base in solid form to a gaseous acid in a substantially dry environment.
申请公布号
CA2500667(A1)
申请公布日期
2006.09.11
申请号
CA20052500667
申请日期
2005.03.11
申请人
APOTEX PHARMACHEM INC.
发明人
MURTHY, K.S. KESHAVA;REY, ALLAN W.;HORNE, STEPHEN E.;DERDOUR, LOTFI;DATTA, PROBAL KANTI;EHLERT, MARTIN