METHOD FOR OINTMENT PRODUCTION BASED ON LIPOPHILIC AND HYDROPHILIC FRACTIONS FROM DOGWOOD STONES

摘要

FIELD: pharmaceutical industry, in particular production of ointment having antiinflammation and antimicrobial activity. ^ SUBSTANCE: method for ointment production includes extraction of ground dogwood stones with chloroform during certain time followed by solvent removing and isolation of lipophilic fraction. Then dried solvent cake from dogwood stones is extracted with boiled purified water, solvent is removed and hydrophilic fraction is isolated. Further emulsifier, petrolatum and lipophilic fraction taken in specific ratio are fused at certain temperature; mixture is cooled and blended with water purified and heated up to certain temperature; obtained mixture is blended with solution comprising purified hydrophilic fraction, glycerol and water taken in specific ratio. ^ EFFECT: ointment of increased antiinflammation and antimicrobial activity. ^ 2 tbl, 6 ex