发明名称 Process for the purification of substituted benzoxazole compounds
摘要 The present invention provides processes for the purification of substituted benzoxazole compounds, and in particular 2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl-benzooxazol-5-ol. The processes include recrystallizing the compound from a solution comprising acetone and acetonitrile; treating the crude purified product with a clarifying agent in a solution comprising ethyl acetate, and precipitating or triturating the compound from a mixed solvent system.
申请公布号 US2006199967(A1) 申请公布日期 2006.09.07
申请号 US20060369113 申请日期 2006.03.06
申请人 WYETH 发明人 IERA SILVIO
分类号 C07D263/60 主分类号 C07D263/60
代理机构 代理人
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