发明名称 |
HEK293 CELL LINE FOR RETRIEVING HIGH-EFFICIENCY INHIBITOR FOR T-TYPE alpha1H CALCIUM CHANNEL AND STUDYING THE INHIBITOR'S WIDE-RANGE PROPERTIES |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new-character cell line transduced with a calcium channel, and to provide a high-efficiency method for retrieving a T-type α1H calcium channel inhibitor based on the cell line. <P>SOLUTION: The cell line is provided, being such that a vector containing a gene encoding a potassium channel is transduced into a cell expressing the T-type α1H calcium channel. The method for retrieving a T-type α1H calcium channel inhibitor using the cell line is also provided. The cell line is usefully usable for the high-efficiency retrieve of T-type α1H calcium channel inhibitor candidates, therefore the development of curatives for many diseases caused by the expression abnormalities of the T-type α1H calcium channel can be accelerated. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
申请公布号 |
JP2006230393(A) |
申请公布日期 |
2006.09.07 |
申请号 |
JP20050117195 |
申请日期 |
2005.04.14 |
申请人 |
KOREA INST OF SCIENCE & TECHNOLOGY |
发明人 |
JEONG SEONG-WOO;LEE JUNG-HA;PARK BYONG-GON;EDWARD PEREZ-REYES;KIM DONG JIN;SHIN HEE SUP |
分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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