发明名称 |
Non-peptide GNRH agents, methods and intermediates for their preparation |
摘要 |
Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.
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申请公布号 |
US7101878(B1) |
申请公布日期 |
2006.09.05 |
申请号 |
US20010763216 |
申请日期 |
2001.02.20 |
申请人 |
AGOURON PHARMACEUTICALS, INC. |
发明人 |
ANDERSON MARK BRIAN;VAZIR HARESH N.;LUTHIN DAVID ROBERT;PADERES GENEVIEVE DEGUZMAN;PATHAK VED P.;CHRISTIE LANCE CHRISTOPHER;HONG YUFENG;TOMPKINS EILEEN VALENZUELA;LI HAITAO;FAUST JAMES |
分类号 |
C07D405/12;A61K31/34;A61K31/505;A61P5/04;C07D307/68 |
主分类号 |
C07D405/12 |
代理机构 |
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