| 发明名称 |
TNF-alphavariants |
| 摘要 |
The invention relates to novel proteins with TNF-alpha antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNF-alpha related disorders, such as rheumatoid arthritis.
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| 申请公布号 |
US7101974(B2) |
申请公布日期 |
2006.09.05 |
| 申请号 |
US20010981289 |
申请日期 |
2001.10.15 |
| 申请人 |
XENCOR |
发明人 |
DAHIYAT BASSIL I.;FILIKOV ANTON |
| 分类号 |
C07K17/00;C12N15/09;A61K38/00;A61K38/19;A61K38/22;A61P1/04;A61P17/06;A61P19/02;A61P25/00;A61P25/02;A61P29/00;A61P31/04;A61P35/00;A61P35/02;A61P37/06;C07K14/525;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;G01N33/53 |
主分类号 |
C07K17/00 |
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