发明名称 |
Pyrrolotriazine kinase inhibitors |
摘要 |
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
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申请公布号 |
US7102002(B2) |
申请公布日期 |
2006.09.05 |
申请号 |
US20050152650 |
申请日期 |
2005.06.14 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CAI ZHEN-WEI;LOMBARDO LOUIS J.;BHIDE RAJEEV S.;QIAN LIGANG;WEI DONNA D.;BARBOSA STEPHANIE |
分类号 |
C07D487/04;A61K31/53;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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