5-oxo and 5-thio derivatives of 5H-indeno'1,2-bipyridine with adenosine A2a receptor binding and phosphodieterase inhibiting activity for the treatment of neurodegenerative disorders and inflammation related diseases

摘要

This invention provides novel arylindenopyridines of the formula: , and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by reducing PDE activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.