摘要 |
Triazole derivatives of structural formula (I) are selective inhibitors of the 11beta-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM. |
申请人 |
MERCK & CO. INC |
发明人 |
WADDELL, SHERMAN, T.;SANTORELLI, GINA, M.;MALETIC, MILANA, M.;LEEMAN, AARON, H.;XIN GU;GRAHAM, DONALD, W.;BALKOVEC, JAMES, M.;ASTER, SUSAN, D. |