摘要 |
Methods and kits are provided for detection of specific polymorphisms that predispose towards osteoporosis and/or are indicative of likely response to treatment. Particular genes analysed are i) calcitonin Receptor; Vitamin D Receptor; Estrogen Receptor; Collagen I A1; and/or ii) Osteoprotegerin, LRP5, CYP17, CYP19 and MTHFR genes. The two groups may be analysed in separate multiplex amplification reactions on a sample. |