发明名称 |
MASS SPECTROMETRY OF ARGININE-CONTAINING PEPTIDES |
摘要 |
Peptides can be derivatised such that, when ionised and analysed by mass spectrometry, those containing arginine residues give characteristic peak patterns. Peaks corresponding to arginine-containing peptides can therefore be selected from a mass spectrum in order to simplify and improve peptide analysis. Suitable labels give derivatised peptides that have the ability to form both a stabilised ion species ([P]+) and a protonated ion molecular species ([P+H]+) that differ by one average mass unit. A characteristic peak pattern is seen. |
申请公布号 |
EP1695090(A1) |
申请公布日期 |
2006.08.30 |
申请号 |
EP20040806028 |
申请日期 |
2004.12.08 |
申请人 |
OXFORD GENE TECHNOLOGY IP LIMITED |
发明人 |
WHEELER, SUSAN;SHCHEPINOV, MIKHAIL, SERGEEVICH;SOUTHERN, EDWIN, MELLOR |
分类号 |
G01N33/68;C07K1/13;C12Q1/68 |
主分类号 |
G01N33/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|