发明名称 Methods of using and compositions comprising (-)030(3,4-dimethoxy-phenyl)-3-(1-oxo 1,3-dihydro-isoindol-2-yl)-propionamide
摘要 Enantiomerically pure (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide, prodrugs, metabolites, polymorphs, salts, solvates, and clathrates thereof are discussed. Methods of treating and/or preventing various diseases and disorders, such as those ameliorated by the reduction of levels of TNF-alpha or the inhibition of PDE4, are also disclosed.
申请公布号 ZA200503926(B) 申请公布日期 2006.08.30
申请号 ZA20050003926 申请日期 2005.05.16
申请人 CELGENE CORPORATION 发明人 MULLER, GEORGE, W.;CHEN, ROGER, S.
分类号 A61K;A61K31/40;A61K31/4035;C07D 主分类号 A61K
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