STABILISED PHARMACEUTICAL COMPOSITIONS ON THE BASIS OF POLYOXYETHYLATED CASTOR OIL AND METHOD FOR MANUFACTURING THE SAME

摘要

The invention relates to a stabilised pharmaceutical composition comprising a pharmaceutically active substance poorly soluble in water, a solubilising agent with a low content of both basic and acidic compounds and a polar organic solvent, in particular a stabilised injection concentrate, methods for preparing such stabilised pharmaceutical compositions and the use of a solubilising agent with a low content of both basic and acidic compounds to stabilise pharmaceutical compositions for pharmaceutically active substances.