QUINOLINE DERIVATIVES AND USE THEREOF AS ANTITUMOR AGENTS

摘要

The invention provides compounds of formula (I):wherein Y is F, Cl, Br, methyl or methoxy ; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula (I) or a salt thereof, intermediates useful for preparing a compound of formula (1) , and therapeutic methods comprising administering a compound of formula (I) or a salt thereof to a mammal in need thereof.