| 摘要 |
The present invention is related to thiazolidine carboxamide derivatives of formula (II) for the treatment and/or prophylaxis of preterm labor, premature birth, dysmenorrhea and for stopping labor prior to cesarean delivery.G is selected from the group consisting of C-C-alkyl aryl, C-C-alkyl heteroaryl, C-C-alkyl cycloalkyl, C-C-alkyl heteroaryl, aryl, heteroaryl, C-C-cycloalkyl or -heterocycloalkyl, said cycloalkyl or aryl or heteroaryl groups may be fused with cycloalkyl or aryl or heteroaryl groups. Ris selected from the group consisting of aryl, heteroaryl, C-C-cycloalkyl or - heterocyclo-alkyl, said (hetero)cycloalkyl or aryl or heteroaryl groups may be fused with (hetero)cycloalkyl or aryl or heteroaryl groups. Ris selected from the group consisting of H, carboxy, acyl, alkoxycarbonyl, aminocarbonyl, C-C-alkyl carboxy, C-C-alkyl acyl, C-C-alkyl alkoxycarbonyl, C-C-alkyl aminocarbonyl, C-C-alkyl acyloxy, C-C-alkyl acylamino, C-C-alkyl ureido, C-Calkyl amino, C-C-alkyl alkoxy, C-C-alkyl sulfanyl, C-C-alkyl sulfinyl, C-C-alkyl sulfonyl, C-C-alkyl sulfonylamino, C-C-alkyl sulfonyloxy, C-C-alkyl, C-C-alkenyl, C-C-alkynyl, aryl, heteroaryl, C-C-cycloalkyl, heterocycloalkyl, C-C-alkyl aryl, C-C-alkyl heteroaryl, C-C-alkyl cycloalkyl, C-C-alkyl heterocycloalkyl, C-C-alkenyl aryl, C-C-alkenyl heteroaryl, C-C-alkynyl aryl, or C-C-alkynyl heteroaryl. |
