A PHARMACEUTICAL COMPOSITION COMPRISING RETINOID FOR PREVENTION AND TREATMENT OF VITILIGO

摘要

The present invention relates to a pharmaceutical composition for the prevention and treatment of vitiligo comprising retinoid as an effective ingredient, precisely a pharmaceutical composition for the prevention and treatment of vitiligo designed to effectively work for vitiligo caused by apoptosis or necrosis of melanocytes by increasing the cell density by reducing apoptosis of human keratinocytes. The pharmaceutical composition of the invention containing retinoid as an effective ingredient not only prevents skin atrophy caused by corticosteroid, a conventional treatment agent of vitiligo, but also inhibits apoptosis of melanocytes and thus improving pigmentation, so that it can be effectively used for the prevention and treatment of vitiligo.