发明名称 |
METHOD OF PASSIVE IMMUNIZATION AGAINST DISEASE OR DISORDER CHARACTERIZED BY AMYLOID AGGREGATION WITH DIMINISHED RISK OF NEUROINFLAMMATION |
摘要 |
Unglycosylated anti-amyloid antibodies maintained all the antigen recognition functions of the native glycosylated anti-amyloid antibodies but without, or with a much reduced, property of triggering Fc receptor-mediated inflammation response in the brain. Such unglycosylated antibodies can be used in a method for preventing, inhibiting, or treating a disease or disorder characterized by amyloid aggregation with a diminished risk of triggering or exacerbating neuroinflammation. |
申请公布号 |
WO2005120571(A3) |
申请公布日期 |
2006.08.24 |
申请号 |
WO2005US19617 |
申请日期 |
2005.06.06 |
申请人 |
RAMOT AT TEL AVIV UNIVERSITY LTD.;GERAGHTY, ERIN;SOLOMON, BEKA;REBE, SABINA |
发明人 |
SOLOMON, BEKA;REBE, SABINA |
分类号 |
G01N33/53;A61K39/00;A61K39/395;A61K45/00;C07K16/18 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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