NOVEL PYRIDINE OXIDE COMPOUND, AND PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE CARBOXYLIC ACID DERIVATIVE WITH THE USE OF THE SAME

摘要

Pyridine oxide compounds of general formula (I), optically active forms thereof, and their salts or hydrates; and performed in the presence of any of these as a catalyst, (1) a process for producing an ester or amide compound from a carboxylic acid equivalent and an alcohol or amine, (2) an asymmetric esterification reaction, and (3) an asymmetric amidation reaction. [Chemical formula 1] wherein R<SUP>1</SUP>s may be identical with or different from each other and each is an alkyl, an aromatic ring group, a heterocyclic group, carboxyl, ester, cyano, a halogen atom, an oxygen atom, a sulfur atom or a nitrogen atom; R<SUP>2</SUP>s may be identical with or different from each other and each is a hydrogen atom, an alkyl, an aromatic ring group, a heterocyclic group, carboxyl, ester, cyano, a halogen atom, an oxygen atom, etc.; and R<SUP>3</SUP>s and R<SUP>4</SUP>s may be identical with or different from each other and each is a hydrogen atom, an alkyl, an aromatic ring group, a heterocyclic group, carboxyl, ester, cyano, a halogen atom, an oxygen atom, etc.