发明名称 |
Facs assisted methods for introducing individual chromosomes into cells |
摘要 |
The present invention provides methods and apparatus for the delivery of at least one chromosome into a cell. Invention methods and apparatus employ FACS or MACS technology for rapidly processing cells and for confirming the introduction of chromosome(s) into a cell. The introduction of the chromosome(s) into the cell is mediated by one or more of a laser, a linear accelerator or electrically induced fusion of a cell and encapsulated chromosome(s). Invention methods provide for the rapid and reliable processing associated with FACS and MACS technology to process thousands of cells a minute, thereby enabling large scale gene transfer. |
申请公布号 |
AU785026(B2) |
申请公布日期 |
2006.08.24 |
申请号 |
AU20000019330 |
申请日期 |
1999.12.03 |
申请人 |
GENETRONICS, INC. |
发明人 |
EDWARD M. NOLAN;DIETMAR P. RABUSSAY;GUNTER A. HOFMANN |
分类号 |
C12N15/87;C07K14/78;C07K16/28;G01N33/68 |
主分类号 |
C12N15/87 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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