| 摘要 |
The invention relates to 5,6-diphenylpyridine-3-carboxamide derivatives of general formula (I): where: R<SUB>1 </SUB>represents hydrogen or a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl; R<SUB>2 </SUB>represents: a monoazo saturated heterocycle of 5 to 7 atoms, the nitrogen atom being substituted with a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkanoyl; NR<SUB>10</SUB>R<SUB>11</SUB>; a nonaromatic (C<SUB>3</SUB>-C<SUB>10</SUB>) carbocycle more than tri-substituted with (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl; a nonaromatic (C<SUB>11</SUB>-C<SUB>12</SUB>) carbocycle unsubstituted or mono- or polysubstituted with (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl; a monooxygenated saturated heterocycle with 5 to 7 atoms, more than tri-substituted with (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl; or R<SUB>1 </SUB>and R<SUB>2</SUB>, together with the nitrogen atom to which the above are bonded, form a 4-disubstituted piperidin- 1 -yl group; the salts, solvates and hydrates thereof. The invention further relates to a method for production and therapeutic application thereof.
|
