发明名称 |
INHIBITOR PEPTIDES |
摘要 |
A mitogen activated protein kinase inhibitor peptide which is covalently coupled to a fluorophore/with beta galactosidase or biotinyl enzymes, is new. A mitogen activated protein kinase inhibitor peptide which is covalently coupled to a fluorophore/with beta galactosidase or biotinyl enzymes. The enzymatic sequence is optionally surrounded by spacer. The export and localization sequence for intracellular signalling. The amino acids corresponding to docking domain of a mitogen activated protein kinase and allows the penetration of HIV-type I trans activating transcriptional activator protein in a cell. Independent claims are also included for: (1) a nucleic acid encoding the peptide; (2) a expression vector; and (3) a kit comprising the peptide and/or the expression vector. |
申请公布号 |
CA2597020(A1) |
申请公布日期 |
2006.08.24 |
申请号 |
CA20062597020 |
申请日期 |
2006.02.16 |
申请人 |
UNIVERSITE PIERRE ET MARIE CURIE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
CABOCHE, JOCELYNE;VANHOUTTE, PETER |
分类号 |
C12N15/62;A01K67/027;A61K47/48 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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