发明名称 INHIBITOR PEPTIDES
摘要 A mitogen activated protein kinase inhibitor peptide which is covalently coupled to a fluorophore/with beta galactosidase or biotinyl enzymes, is new. A mitogen activated protein kinase inhibitor peptide which is covalently coupled to a fluorophore/with beta galactosidase or biotinyl enzymes. The enzymatic sequence is optionally surrounded by spacer. The export and localization sequence for intracellular signalling. The amino acids corresponding to docking domain of a mitogen activated protein kinase and allows the penetration of HIV-type I trans activating transcriptional activator protein in a cell. Independent claims are also included for: (1) a nucleic acid encoding the peptide; (2) a expression vector; and (3) a kit comprising the peptide and/or the expression vector.
申请公布号 CA2597020(A1) 申请公布日期 2006.08.24
申请号 CA20062597020 申请日期 2006.02.16
申请人 UNIVERSITE PIERRE ET MARIE CURIE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 发明人 CABOCHE, JOCELYNE;VANHOUTTE, PETER
分类号 C12N15/62;A01K67/027;A61K47/48 主分类号 C12N15/62
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