发明名称 THIENOPYRIDYL COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF
摘要 The present invention discloses fused thienopyridyl compounds of general formula (I), wherein X<SUB>1</SUB>-X<SUB>6</SUB>, R<SUB>5</SUB>-R<SUB>7</SUB>, Z<SUB>1</SUB> and L are as defined in the description. The resent invention also discloses a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain, urinary incontinence, bladder overactivity, and inflammatory thermal hyperalgesia in mammals, and pharmaceutical compositions including those compounds.
申请公布号 WO2006063178(A3) 申请公布日期 2006.08.24
申请号 WO2005US44500 申请日期 2005.12.07
申请人 ABBOTT LABORATORIES;TURNER, SEAN, C.;JINKERSON, TAMMIE, K.;GOMTSYAN, ARTHUR, R.;LEE, CHIH-HUNG 发明人 TURNER, SEAN, C.;JINKERSON, TAMMIE, K.;GOMTSYAN, ARTHUR, R.;LEE, CHIH-HUNG
分类号 C07D495/04;A61K31/4365;A61P13/10;A61P29/00 主分类号 C07D495/04
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