TXR1 AND ENHANCED TAXANE SENSITIVITY BASED ON THE MODULATION OF A PATHWAY MEDIATED THEREBY

摘要

Methods and compositions for enhancing taxane sensitivity are provided. Aspects of the subject methods include administering to a subject a txr1pathway modulatory agent in conjunction with a taxane. Also provided are txr1 polypeptides and nucleic acids encoding the same. The subject methods and compositions find use in a variety of different applications.