| 发明名称 |
METHODS AND COMPOSITIONS FOR INHIBITING C-MET DIMERIZATION AND ACTIVATION |
| 摘要 |
<p>The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating c-met dimerization and/or binding of ligand to c-met using a c-met antagonist that disrupts c-met multimerization.</p> |
| 申请公布号 |
EP1692178(A1) |
申请公布日期 |
2006.08.23 |
| 申请号 |
EP20040813660 |
申请日期 |
2004.12.10 |
| 申请人 |
GENENTECH, INC. |
发明人 |
WICKRAMASINGHE, DINELI M.;KONG-BELTRAN, MONICA |
| 分类号 |
C07K16/18;A61K38/00;A61K38/03;A61K38/08;A61K38/17;A61K38/18;C07K14/475;C07K16/22;C07K16/32;G01N33/68 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
