| 发明名称 |
PARATHYROID HORMONE RECEPTOR ACTIVATION AND HEMATOPOIETIC PROGENITOR CELL EXPANSION |
| 摘要 |
<p>The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.</p> |
| 申请公布号 |
EP1545603(A4) |
申请公布日期 |
2006.08.23 |
| 申请号 |
EP20030771904 |
申请日期 |
2003.07.25 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
CALVI, LAURA, M.;ADAMS, GREGOR, B.;KRONENBERG, HENRY, M.;SCADDEN, DAVID, T. |
| 分类号 |
A61K38/29;A61K39/38;C07K14/72;C12N5/02;C12N5/0789;(IPC1-7):A61K39/38;A61K35/28;C12N5/00;A61K39/00;A61K35/26 |
主分类号 |
A61K38/29 |
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