发明名称 |
NOVEL VINYL SULFIDE COMPOUNDS AND A PROCESS FOR THEIR PREPARATION |
摘要 |
Vinyl sulfides bearing protected arlyoxy substituents and a process for thei r preparation are provided. In the process a vinyl sulfide is formed by coupling a ketone compound and a thioester compound with a low valent titanium reagent to form both carbon-carbon bonds in the same step. The vinyl sulfide compounds are useful as intermediates which are convertible into triggerable sulfur-substituted dioxetanes by addition of oxygen to the double bond. The sulfur-substituted dioxetanes additionally are useful for producing chemiluminescence or for further conversion into triggerable alkoxy, alkenyloxy, alkynyloxy, aryloxy, aralkyloxy or acyloxy-substituted dioxetanes. Triggerable dioxetanes are useful for producing chemiluminescence and in detecting activating agents in assays such as immunoassays and nucleic acid hybridization assays.
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申请公布号 |
CA2222788(C) |
申请公布日期 |
2006.08.22 |
申请号 |
CA19962222788 |
申请日期 |
1996.06.19 |
申请人 |
LUMIGEN, INC. |
发明人 |
EICKHOLT, ROBERT A.;ARGHAVANI, ZAHRA;AKHAVAN-TAFTI, HASHEM |
分类号 |
C07C323/56;C07D521/00;C07B61/00;C07C319/20;C07C323/11;C07C323/15;C07C323/16;C07F7/18;C07F9/12;C07H15/203;C09K11/07 |
主分类号 |
C07C323/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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