发明名称 |
Inhibitors of the inositol polyphosphate 5-phosphatase SHIP2 molecule |
摘要 |
The present invention is related to an inhibitor of the inositol polyphosphate 5-phosphatase SHIP2 protein or its encoding nucleotide sequence identified by SEQ ID NO. 1 or of SHIP2 mRNA expression. The present invention is also related to a pharmaceutical composition comprising said inhibitor and an adequate pharmaceutically acceptable carrier or diluent and to a non-human knock-out mammal comprising homozygously or heterozygously a partial or total deletion in its genome of the inositol polyphoshate 5-phosphatase SHIP2 nucleotide sequence.
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申请公布号 |
US7094546(B2) |
申请公布日期 |
2006.08.22 |
申请号 |
US20030742431 |
申请日期 |
2003.12.19 |
申请人 |
EUROSCREEN, S.A. |
发明人 |
ERNEUX CHRISTOPHER;SCHURMANS STEPHANE |
分类号 |
A01K67/027;C12Q1/68;A61K31/35;A61K33/24;A61K38/55;A61K45/00;A61K48/00;A61P3/10;A61P43/00;C07H21/04;C12N1/20;C12N9/99;C12N15/00;C12N15/09;C12Q1/42;G01N33/15;G01N33/50;G01N33/53;G01N33/566 |
主分类号 |
A01K67/027 |
代理机构 |
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主权项 |
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地址 |
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