发明名称 |
8-{4-[3-(5-FLUORO-1H-INDOL-3-YL)PROPYL]PIPERAZIN-1-YL}-2-METHYL-4H-BENZO[1,4]OXAZINE-3-ONE MESYLATE WITH HIGH AFFINITY TO DOPAMINE RECEPTOR D2 AND SEROTONIN REUPTAKE SITE |
摘要 |
FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention relates to new derivative of phenylpiperazine mesylate of the formula: possessing preferable properties as compared with form of a free base of the same compound. Also, invention describes a pharmaceutical composition and a method for inhibition of activity of dopamine D2-receptors and site of serotonin reuptake. ^ EFFECT: valuable pharmacological properties of derivatives. ^ 3 cl, 1 ex |
申请公布号 |
RU2281945(C2) |
申请公布日期 |
2006.08.20 |
申请号 |
RU20030114440 |
申请日期 |
2002.02.19 |
申请人 |
SOLVEJ FARMAS'JUTIKALS B.V. |
发明人 |
BAKKER KORNELIS |
分类号 |
C07D413/12;A61K31/538;A61P25/00;A61P25/18;A61P25/22;A61P25/24;A61P43/00 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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