PREVENTIVE OR THERAPEUTIC AGENT FOR STROKE OR SEQUELA OF STROKE CONTAINING 1-AMINOCYCLOPROPANE CARBOXYLIC ACID OR THE LIKE AS MAIN INGREDIENT

摘要

PROBLEM TO BE SOLVED: To provide a new preventive or therapeutic agent for stroke or sequelae of stroke. SOLUTION: The preventive or therapeutic agent for stroke or sequelae of stroke contains a compound selected from 1-aminocyclopropane carboxylic acid, its prodrug and pharmaceutically permissible salts and hydrates of those as a main ingredient. For example, 1-aminocyclopropane carboxylic acid hydrochloride-hydrate suppresses 90% onset of stroke in 50 mg/kg dose which corresponds to≤1/100 acute toxicity. In the case of onset of stroke, the sequelae are slight. COPYRIGHT: (C)2006,JPO&NCIPI