发明名称 ANTIBODIES TO TGFBETA
摘要 The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF.beta.), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGF.beta.1, TGF.beta.2, and TGF.beta.3, so-called 'pan-specific' antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
申请公布号 CA2930677(A1) 申请公布日期 2006.08.17
申请号 CA20062930677 申请日期 2006.02.08
申请人 GENZYME CORPORATION;OPTEIN, INC. 发明人 LEDBETTER, STEVEN R.;HART, CELIA P.;HOLGATE, ROBERT G.;JERMUTUS, LUTZ U.;BUCHANAN, CATRIONA L.;DUNCAN, ALEXANDER R.;FINCH, DONNA K.
分类号 C07K16/22;A61K39/395;A61P19/04;A61P35/00;A61P37/06;C12N15/13;C12P21/08 主分类号 C07K16/22
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