发明名称 |
Substituted thienyl and furyl acylguanidines and methods of their use as beta-secretase modulators |
摘要 |
The present invention provides a substituted thienyl or furyl acylguanidine compound of formula I The present invention also provides methods for the inhibition of beta-secretase (BACE) and for the treatment of beta-amyloid deposits and neurofibrillary tangles.
|
申请公布号 |
US2006183792(A1) |
申请公布日期 |
2006.08.17 |
申请号 |
US20060352646 |
申请日期 |
2006.02.13 |
申请人 |
WYETH |
发明人 |
FOBARE WILLIAM F.;SOLVIBILE WILLIAM R.JR. |
分类号 |
A61K31/381;C07D333/38 |
主分类号 |
A61K31/381 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|