| 发明名称 |
SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS |
| 摘要 |
<p>The present invention relates to a series of substituted bis aryl and heteroaryl compounds of formula (I): Wherein X, Y, Z, A, B, D, Ar, R<SUB>1</SUB> and R<SUB>2</SUB> are as defined herein. The compounds of this invention are selective 5HT<SUB>2A</SUB> antagonists, and are therefore, useful in treating a variety of diseases including but not limited to a wide variety of sleep disorders as disclosed and claimed herein.</p> |
| 申请公布号 |
WO2006086705(A1) |
申请公布日期 |
2006.08.17 |
| 申请号 |
WO2006US04879 |
申请日期 |
2006.02.10 |
| 申请人 |
AVENTIS PHARMACEUTICALS INC.;FINK, DAVID MARK;SMITH, HELEN KATHERINE;TODD, RICHARD SIMON;EASTWOOD, PAUL ROBERT;HUNT, HAZEL |
发明人 |
FINK, DAVID MARK;SMITH, HELEN KATHERINE;TODD, RICHARD SIMON;EASTWOOD, PAUL ROBERT;HUNT, HAZEL |
| 分类号 |
C07D209/08;C07D231/56;C07D235/26;C07D239/96;C07D249/18;C07D263/58;C07D265/34;C07D277/68;C07D401/14;C07D405/04;C07D409/04;C07D409/14;C07D413/12;C07D413/14;C07D471/04 |
主分类号 |
C07D209/08 |
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