发明名称 FUMARIC ACID DERIVATIVES AS NF-KAPPAB INHIBITORS
摘要 The invention relates to the use of at least one fumaric acid derivative as an NF-kappaB inhibitor for the treatment of diseases such as progressive systemic sclerodermia, mottled skin, Behet's disease, ulcerative colitis, vasculitis, osteoarthritis, gout, arteriosclerosis, Reiter's syndrome, types of encephelitis, endotoxin shock, pneumonia, encephalomyelitis, anorexia nervosa, hepatitis, mesangial nephritis, reperfusion syndrome, cytomegalvirus retinopathy, adenoviral diseases such as adenoviral catarrhal fever, AIDS, neuralgia, inflammatory demyelination polyneuropathy, multiplex type of mononeuropathy, mucoviscidosis, Bechterew's disease, endobrachyoesophagus, EBV (Epstein Barr virus) infection, interstitial cystitis, pancreatic diabetes type II, the radiation sensitisation of malignant tumours, and the multiple resistance of malignant cells in cancers.
申请公布号 YU55903(A) 申请公布日期 2006.08.17
申请号 YU2003P000559 申请日期 2002.01.08
申请人 FUMAPHARM 发明人 JOSHI, RAJENDRA KUMAR;STREBEL, HANS-PETER;PETZELBAUER, PETER
分类号 A61K9/22;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K9/50;A61K9/62;A61K31/194;A61K31/225;A61K47/04;A61K47/12;A61K47/32;A61K47/36;A61K47/38;A61P1/04;A61P1/16;A61P9/00;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P19/02;A61P19/06;A61P19/08;A61P25/00;A61P31/00;A61P31/04;A61P31/12;A61P35/00;A61P39/02 主分类号 A61K9/22
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