| 发明名称 |
Azolylacylguanidines as beta-secretase inhibitors |
| 摘要 |
The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit beta-secretase (BACE) and treat beta-amyloid deposits and neurofibrillary tangles.
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| 申请公布号 |
US2006183790(A1) |
申请公布日期 |
2006.08.17 |
| 申请号 |
US20060352820 |
申请日期 |
2006.02.13 |
| 申请人 |
WYETH |
发明人 |
COLE DEREK C.;MANAS ERIC S.;JENNINGS LEE D.;LOVERING FRANK E.;STOCK JOSEPH R.;MOORE WILLIAM J.;ELLINGBOE JOHN W.;CONDON JEFFREY S.;SUKHDEO MOHANI N.;ZHOU PING;WU JUNJUN;MORRIS KOI M. |
| 分类号 |
A61K31/40;C07D207/22 |
主分类号 |
A61K31/40 |
| 代理机构 |
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