| 发明名称 |
Ligands to enhance cellular uptake of biomolecules |
| 摘要 |
The present invention relates to the design and synthesis of homogeneous A-L-P constructs, which contain a hepatic ligand to direct an oligomer or "payload" to a hepatocyte intracellularly via a receptor-mediated, ligand-directed pathway.
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| 申请公布号 |
US2006183886(A1) |
申请公布日期 |
2006.08.17 |
| 申请号 |
US20050256476 |
申请日期 |
2005.10.21 |
| 申请人 |
CELL WORKS THERAPEUTICS, INC., A DELAWARE CORPORATION |
发明人 |
TSO PAUL O.;DUFF ROBERT;ZHOU YUANZHONG;DEAMOND SCOTT;ROBY CLINTON |
| 分类号 |
C07K14/005;C12N15/09;A61K31/7088;A61K47/48;A61P1/16;A61P31/12;C07H15/18;C07H21/00;C07K16/10;C12N15/11 |
主分类号 |
C07K14/005 |
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