摘要 |
A high throughput screening method. At least one liquid sample is provided that includes an analyte that directly or indirectly produces a detectable characteristic in one or more first assays. A plurality of through holes is filled with portions of the liquid sample in a testing assembly that has a pair of opposing surfaces, each through hole extending from one of the opposing surfaces to the other of the opposing surfaces, with the through holes arranged in group. Surface tension holds the respective portions in the respective plurality of through holes. A detection is made of which of the through holes contains a liquid sample portion that includes said analyte. The detectable characteristic may be produced in various assays such as an absorbance transcription assay, a fluorescent transcription assay, a fluorescent secreted enzyme assay, or a microorganism screening assay.
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