| 摘要 |
The present invention relates to methods for treating cancers by manipulating a target gene expression by up-regulation, silencing and/or down-regulation of the gene, such as EGFR-RP, TRA1, MFGE8, TNFSF13 and ZFP236, respectively. The methods are useful in treating cancers and/or inhibiting tumor growth by enhancing expression of a gene that is validated as a target such as ICT1030, for protein, peptide drug and gene therapy modalities; or by RNA interference to silence and/or down-regulate targets such as ICT1024, ICT1025 and ICT1031 and ICB1003 that are validated for antibody, small molecule and other inhibitor drug modalities.
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| 申请人 |
INTRADIGM CORPORATION;LU, PATRICK, Y.;XIE, FRANK, Y.;WOODLE, MARTIN, C.;LIU, YIJIA;TANG, QUINN Q.;XU, JUN |
发明人 |
LU, PATRICK, Y.;XIE, FRANK, Y.;WOODLE, MARTIN, C.;LIU, YIJIA;TANG, QUINN Q.;XU, JUN |
