NEUROSPHERE-FORMING AGENT

摘要

[PROBLEMS] To provide a neurosphere-forming agent capable of highly efficiently forming neurospheres and a medicinal composition capable of efficiently improving a nerve function damaged by a nerve disturbance. [MEANS FOR SOLVING PROBLEMS] Mouse CD8a-positive dendritic cells, matured dendritic cells and Notch-positive dendritic cells are separated and a neurosphere-forming agent or a medicinal composition comprising one of more of these dendritic cells is prepared. By culturing the dendritic cells contained in the neurosphere-forming agent together with neural stem cells, neurospheres can be formed at a high efficiency. By administering the medicinal composition to an injured part in nerve, the damaged nerve function can be efficiently improved.