发明名称 Selection probe amplification
摘要 Multiple unique selection probes are provided in a single medium. Each selection probe has a sequence that is complementary to a unique target sequence that may be present in a sample under consideration. For example, each selection probe may be complementary to a sequence that includes one of the SNPs used to genotype an organism. Single-stranded selection probes anneal or hybridize with sample sequences having the unique target sequences specified by the selection probe sequences. Sequences from the sample that do not anneal or hybridize with the selection probes are separated from the bound sequences by an appropriate technique. The bound sequences can then be freed to provide a mixture of isolated target sequences, which can be used as needed for the application at hand.
申请公布号 US2006183132(A1) 申请公布日期 2006.08.17
申请号 US20050058432 申请日期 2005.02.14
申请人 PERLEGEN SCIENCES, INC. 发明人 FU GLENN;STUVE LAURA;SHEEHAN JOHN;OLLMANN AMY;SHEN NAIPING;SPARKS ANDREW B.;BALLINGER DENNIS
分类号 C12Q1/68;C12P19/34 主分类号 C12Q1/68
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