METHOD FOR IDENTIFYING THE RISK OF PRETERM DELIVERY

摘要

Methods provided herein can identify subjects at risk for preterm delivery, including those at risk for preterm delivery with inflammation. In one embodiment, the methods utilize small molecule profiles of metabolites in pregnant subjects. For example, the presence, absence, or amount of amino acids and/or energy-producing carbon sources are determined and compared to amounts found in subjects that have undergone a full-term delivery. Changes in the presence, absence, or amount of these small molecules may indicate that the subject is at increased risk for having a preterm delivery, or a preterm delivery without inflammation.