| 摘要 |
<p>A cooling method for selective disruption of lipid rich cells in a non-infant human treatment subject and systems 100 for providing feedback information in connection with the selective disruption of said lipid rich cells, comprising: at least one non-invasive cooling element 110 proximate to an application site of the treatment subject, where the cooling element is effective to decrease the temperature beneath the application site, and where the temperature decrease is sufficient to disrupt and thereby reduce lipid rich cells beneath the application site. At least one feedback device 120 is provided in communication with the at least one cooling element, where the feedback device either provides feedback information sufficient to confirm that non lipid rich cells proximate to the cooling element are not disrupted or provides feedback information sufficient to confirm that the temperature decrease is sufficient to disrupt and thereby reduce lipid rich cells beneath the application site. The feedback device comprises an ultrasound based feedback device having a transducer that is less than approximately 2 cm in diameter in contact with the at least one cooling element. The method and systems provide a means for selectively damaging lipid-rich cells, such as adipocytes comprising the subcutaneous fatty tissue 170, without causing injury to non lipid rich cells, such as the dermis 165 and/or epidermis 160, and offers a non-invasive alternative to conventional liposuction techniques for reduction of fatty tissue.</p> |
