Phosphorus-containing compounds and uses thereof

摘要

This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which: A is absent or is -O-, -S- or -NR²-; Q is absent or (if A is -O-, -S- or -NR²-) Q may be -V-, -OV-, -SV-, or -NR²V-, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR²VA; K is O or S; each occurrence of Y is independently -O-, -S-, -NR²-, or a bond linking a R⁵ moiety to P; each occurrence of R² and R⁵ is independently an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, or H; and each occurrence of R⁶ is independently -PK(YR⁵)(YR⁵), -SO₂(YR⁵) or -C(O)(YR⁵); so long as any R², or R⁵ moiety linked directly to P is not H; wherein two R², R⁵ and/or R⁶ moieties may be chemically linked to one another to form a ring; each occurrence of G is independently -O-, -S-, -NR²- or (M)_x; each occurrence of M is independently a substituted or unsubstituted methylene moiety, and any M-M' moiety may be saturated or unsaturated; each occurrence of x is independently an integer from 1-6; and the other variables are as defined herein.