发明名称 |
Method for labeling DNA and RNA |
摘要 |
A method for fragmenting and labeling nucleic acids is provided. The method comprises maintaining double- and single-stranded nucleic acid molecules in an aerobic or an anaerobic atmosphere, contacting the molecules with hydrogen peroxide and radical generating coordination complexes for a time and at concentrations sufficient to produce aldehyde moieties on the molecules, reacting the aldehyde moieties with amine to produce a condensation product, and labeling the condensation product.
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申请公布号 |
US2006178508(A9) |
申请公布日期 |
2006.08.10 |
申请号 |
US20020057753 |
申请日期 |
2002.01.23 |
申请人 |
BAVYKIN SERGEI;MIRZABEKOV ANDREI D |
发明人 |
BAVYKIN SERGEI;MIRZABEKOV ANDREI D. |
分类号 |
C07H21/04;B01D15/08;B01J20/283;C07H21/00;C12N15/10;C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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