发明名称 |
PARVOVIRUS METHODS AND COMPOSITIONS FOR KILLING NEOPLASTIC CELLS |
摘要 |
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while leaving healthy cells intact. The invention thus comprises a method of killing cancer and other neoplastic and preneoplastic cells by administration of AAV2 virus, viral particles, products or replication incompetent vectors derived there from to said cells, and pharmaceutical compositions comprising the same.
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申请公布号 |
WO2006047301(A9) |
申请公布日期 |
2006.08.10 |
申请号 |
WO2005US37930 |
申请日期 |
2005.10.21 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION;MEYERS, CRAIG;ALAM, SAMINA |
发明人 |
MEYERS, CRAIG;ALAM, SAMINA |
分类号 |
A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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地址 |
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