| 摘要 |
FIELD: organic chemistry, medicine, veterinary. ^ SUBSTANCE: described is complex based on (2,3-dioxypropyl)ortho-titanate-silicate of formula Ti-[O-CH2-CH(OH)-CH2-OH]4.Si-[O-CH2-CH(OH)-CH2-OH]4.12C3H8O.48H2O, obtained by interaction of butylorthotitanate and ethylorthosilicate with glycerol in molar ratio of 1:1:20, respectively, at 100-120°C in vacuum while removing of formed mixture of ethanol and butanol, followed by addition of acidified water with pH 2.5-3.5 and conditioning at 85°C or lower for at least 1.5 hour. Also disclosed is pharmaceutical composition containing aforementioned compound as active ingredient and carrier in ratio (mass %) of active ingredient 0.01-10.00; and balance: carrier. ^ EFFECT: enhanced assortment of biologically active ointment sources of penetrative dermatic action. ^ 2 cl, 7 ex |
