发明名称 AMIDE COMPOUND
摘要 <p>Disclosed is a compound represented by the formula (I) or (II) below, or a salt thereof. [In the formulae, ring A represents an optionally substituted ring (which is not a pyrrolidine, piperidine or piperazine); ring B represents an optionally substituted aromatic ring; ring D represents an optionally substituted ring; R&lt;SUP&gt;1&lt;/SUP&gt; and R&lt;SUP&gt;2&lt;/SUP&gt; independently represent a hydrogen atom or a substituent; R&lt;SUP&gt;3&lt;/SUP&gt; represents a hydrogen atom or a C&lt;SUB&gt;1-6&lt;/SUB&gt; alkyl group, or alternatively it combines with the ring A to form a non-aromatic ring; ring Aa represents an optionally substituted aromatic hydrocarbon; Y represents CH or N; Ra&lt;SUP&gt;1&lt;/SUP&gt; represents an optionally substituted hydrocarbon group; and Ra&lt;SUP&gt;2&lt;/SUP&gt; and Ra&lt;SUP&gt;3&lt;/SUP&gt; independently represent a hydrogen atom or a substituent.] The compound has a DGAT inhibitory effect and is useful for treatment or improvement of diseases or conditions caused by high expression or high activation of DGAT.</p>
申请公布号 WO2006082952(A1) 申请公布日期 2006.08.10
申请号 WO2006JP301942 申请日期 2006.01.31
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;OGINO, MASAKI;NAKADA, YOSHIHISA;SHIMADA, MITSUYUKI;ASANO, KOUHEI;TAMURA, NORIKAZU;MASAGO, MINORI 发明人 OGINO, MASAKI;NAKADA, YOSHIHISA;SHIMADA, MITSUYUKI;ASANO, KOUHEI;TAMURA, NORIKAZU;MASAGO, MINORI
分类号 C07C235/78;A61K31/167;A61K31/196;A61K31/216;A61K31/381;A61K31/40;A61K31/415;A61K31/426;A61K31/427;A61K31/44;A61K31/47;A61K31/505;A61K31/535;A61P1/00;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P13/12;A61P15/00;A61P19/10;A61P21/00;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D207/34;C07D213/75;C07D215/38;C07D231/14;C07D231/38;C07D239/42;C07D277/28;C07D295/12;C07D333/36;C07D409/12;C07D417/12 主分类号 C07C235/78
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