| 摘要 |
A topical formulation for the treatment of urushiol induced contact dermatitis, comprising: (1) a first medicament, wherein the first medicament is represented by the following chemical structure: wherein R<SUB>1-10 </SUB>are the same or different and comprise H, a hydroxy group, a straight or branched alkyl, cycloalkyl, polycycloalkyl, heterocycloalkyl, aryl, alkaryl, aralkyl, alkoxy, alkenyl, alkynyl group containing approximately 1 to approximately 50 carbon atom(s), a silyl or siloxyl group containing approximately 1 to approximately 50 silicon atom(s), and combinations thereof; wherein X<SUB>1-2 </SUB>are the same or different and comprise O, S, or Se; and wherein z is an integer ranging from approximately 1 to approximately 100; and (2) a second medicament, wherein the second medicament is represented by the following chemical structure: wherein R<SUB>1-4 </SUB>are the same or different and comprise H, a hydroxy group, a straight or branched alkyl, cycloalkyl, polycycloalkyl, heterocycloalkyl, aryl, alkaryl, aralkyl, alkoxy, alkenyl, alkynyl group containing approximately 1 to approximately 50 carbon atom(s), a silyl or siloxyl group containing approximately 1 to approximately 50 silicon atom(s), and combinations thereof; wherein X<SUB>1-3 </SUB>are the same or different and comprise O, S, or Se; wherein Z comprises N or P; and wherein D comprises a Group I element, with the provisio that the first medicament and the second medicament cooperatively effectuate substantial removal of urushiol from an affected area of a patient having urushiol induced contact dermatitis.
|
