发明名称 Tumor model with chromosomal rearrangement and uses thereof
摘要 The invention relates to a method for generating a non-human animal model of a chromosomal rearrangement, comprising creating a transgenic non-human mammal expressing a site-specific recombinase under the control of a cell type specific promoter, and having sites recognized by the recombinase present in its genome such that a chromosomal rearrangement is catalysed by the recombinase.
申请公布号 US2006179495(A1) 申请公布日期 2006.08.10
申请号 US20050255618 申请日期 2005.10.21
申请人 MEDICAL RESEARCH COUNCIL 发明人 RABBITTS TERENCE H.
分类号 A01K67/027 主分类号 A01K67/027
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